Fl l p h aTHERAPEUTIC
5555
(213)

Fe br u a r y 2 3 ,

Valley Boulevard.
225-2221

Los Angeles CA 9OG32
TLX. 4997369

19 8 7

o r . J i i m~y Lo r d , Pr e s i de n t
Pi n e Bl u f f Bl o l o gl c a l Pr o d u c t s ,
5 10 Mu l b e r r y St r e e t
Pi n e Bl u f f , Ar k a ns a s 7 16 0 1
I

CORPORATlOy~

I nc .

De a r J i mmy :
pa r i n
Pe r o u r c o n ve r s a t i o n o n Fe b r u a r y 20 , 19 8 7 . pl e a s e r e i n s t a t e t h e He
. _
p l a s ma pr o g r a m a t yo u r Va r n e r Pl a s ma - Gr a dy f a c i l i t y a s s o o n a s p os s i bl e .
I have
n o t i f i e d Al ph a ' s Ma t e r i a l ' s Ma n a g e me n t De pa r t me n t
t o c oor di na t e
t h e de l i ve r y o f a l l i t e ms ne c e s s a r y t o b e gi n t he p r og r a m i mme di a t e l y .
Th e pr o g r a m wi l l r e ma i n i n e f f e c t
p e r i o d , u n l e s s ot h e r wi s e a dv i s e d .
Sh o u l d y o u h a ve
c o n ve n i e n c e .

a ny

q u e s t i on s ,

t hr o u gh t h e r e ma i n d e r

pl e a s e

c ont a c t

me

of

at

y ou r

y o ur

c on t r a c t

ear l i es t

Sl n c e r e l y ,

Mi c ha e l A. Li ndenbaum
Associate
Director,
Plasma

cc:

J.
P.
L.
T.
E.
5.
M.

Procurement

Ca r l i s l e
Ha j du k
Ho u gh t o n
Mc Nl c o l
Ne i l s o n
Si ms
To wns e n d

( 08 0 7 1)

MDi_TPL4A-0380

June

3,

1987

MK. Jim Lord, President
Pine Bluff
Biological
510 Mulberry
Street
Pine Bluff,
AR 71601
Dear

Products,

Inc.

Jim:

This
shall
intent
to
follows :

serve
as written
purchase
heparin

Locat ion:

Term :

of Alpha
Therepeutic
plasma
f r o m Varner

commencing

July

Upon 30 day

notice

1,

as

1987

The consummation
of this
purchase
of heparin
and/or
normal
to execution
of Alpha’s
standard
Agreement
for the Purchase
Plasma by both Alpha and Varner Plasma Inc.
Sincerely,

Associate’Director,

Corporation’s
Plasma
Inc.

Arkansas
Department
of Corrections,
Cummins Unit,
Plasma Center
Grady, AR 71644

One year,

Cancellation:

confirmation
and/or
normal

Plasma

Procurement

plasma
is subject
and Sale of Blood

Rl p h a THERAPEUTIC
5555

ValleV Boulevard,

LOS

i 213) 225. 2221

July

2,

TLX : 4993369

1987

Mr. Jim Lord,
President
Pine Bluff
Biological
510 Mulberry
Street
Pine Bluff,
AR 71601

Dear

Angeles CA 90032

Products,

Inc.

Jim:

This
shall
intent
to
follows:

serve
purchase

Location:

as

written
heparin

confirmation
and/or
normal

Arkansas
Department
Pine Bluff
Diag
Pine Bluff,

of

of Alpha
Therapeutic
plasma
from Varner

Corporation’s

Corrections,
h Womens Unit

,

Term:

6 months,

Cancellation:

commencing

July

Upon 30 day

notice

1,.1987

The consummation
of this
purchase
of heparin
and/or
normal
to execution
of Alpha’s
standard
Agreement
for the Purchase
Plasma by .both Alpha and Varner
Plasma,
Inc.

plasma
is s
and Sale of Blood

Sincerely,

Manager,

Plasma

Procurement

MDLTPLbA-0371

. -

OLFlIpha

THERAPEUTIC

5555 Val l e y

Boul e var d.

( 213; 225- 2221

April

25,

CORPORATION3

LosAnge!es
CA90032
TLX: 4937369

1988

Mr. Jim Lord
Pine Bluff Biological Products, Inc.
510
Mulberry Street
Pine Bluff, AR 71601
c
Dear Jim:
Enclosed please find two (2) originals of Amendment Number One to the
Agreement for the Purchase and Sale of Blood Plasma between Alpha Therapeutic
Corporation and Pine Bluff Biological Products, Inc. and two (2) originals of
Amendment Number One to the Agreement for the Purchase and Sale of Blood
Plasma between Alpha Therapeutic Corporation and Varner Plasma Center, Inc.
Please review and return one signed original of each Amendment to my attention
at your earliest convenience.
Keep the second set of originals for your
records. If you have any questions or if I can be of any assistance, please
call.

Sincerely,

A

Michael A. Lindenbaum
Assoc. Director, Plasma Procurement

MAL:ag

Enc.

MDLTPL4A-0341

AMENDMENT NUMBER ONE
TO
AGREEMENT FOR THE PURCHASE AND SALE
OF BLOOD PLASMA
BETHEEN
ALPHA THERAPEUTI C CORPORATI ON
AND
PI NE BLUFF BI OLOGI CAL PRODUCTS,
( FAYETTEVI LLE,

Thl s

Ame ndme nt

PI NE BLUFF, AND NORTH LI TTLE ROCK)

Numbe r One

Al pha

The r a pe ut f c

Co r por a t i o n,

place

of

at

bus i ne s s

I NC.

a

5 55 5 Val l e y

i s ma de

and e nt e r e d

I nt o

Ca l f f o r ni a Co r po r a t i o n,
Bo ul e v a r d,

Lo s

ul t h

Ang e l e s ,

Ar ka ns as

St r e e t ,

c o r po r at i o n

Pi ne Bl uf f ,

wi t h a pr i nc i pal

pl a c e o f

and
Its

be t we e n

pr l nc l pa l

Ca l l f o r nl a

( he r e i naf t e r r e f e r r e d t o a s "Al pha "> a nd Pt ne Bl uf f Bl ol o g l c a l
an

by

bus l ne s s

9 0 0 32

Pr oduc t s ,
at

510

Inc.,

Mul be r r y

Ar ka ns a s 7 1 60 1 ( he r e f na f t e r r e f e r r e d t o a s "Se l l e r ") .

TNESSETH:
_W_I __
_ _ __ w_

WHEREAS,
f o r t he Pur c ha s e
Ag r e e me nt ") ,

1 , 1987

a nd Sa l e of

Al pha a nd Se l l e r e nt e r e d I nt o a n Ag r e e me nt

Bl o o d Pl a s ma ( he r e i naf t e r r e f e r r e d t o as

"Pl a s ma

and

CIHEREAS,
Pl a s ma Ag r e e me nt
MOM,

o n Aug us t

the

par t i e s

de s i r e

t o ma ke . c e r t a i n c ha ng e s

t o be c o me e f f e c t i v e f r o m Ma r c h 7 ,

THEREFORE,

t e r ms a nd c o ndl t l o ns

I n c ons l de r a t l o n o f

s e t f o r t h he r e t n,

I n and

to

t he

19 8 8 .

t he f or e g oi ng a nd s ubj e c t

t o t he

t he pa r t l e s mut ua l l y a g r e e a s ~fllows:

-l,

MDLTPL4A-0342

Se c t i o n

2. 2. 4

of

t he

I ns e r t e d I n I t s

Pl a s ma
pl a c e

Ag r e e me nt

as

1s

he r e by

t ho ug h f ul ‘ l y s e t

de l e t e d

f or t h

a nd

t he

f o l l owi ng

is

I n t he Pl as ma

Ag r e e me nt

( unde t s c o r l ng l ndl c a t e s c ha ng e s f r o m t he o r i g i nal Pl a s ma Ag r e e me n t ) :

"2 . 2 . 4
Se l l e r a gr e e s t o a l l o w Al pha t o s e t of f a nd de duc t
t he
f ol l o wi ng a mo unt f r o m t he be l ow- l i s t e d Ce nt e r ( s ) pe r ki l o g r am o f
Pl a s ma pur c ha s e d by Al pha f r o m Se l l e r he r e unde r unt t l t he e nt i r e l o a n
Lo a n
Ag r e e me nt
a nd
Pr omf s s o r y
Not e
da t e d
a mo unt s - unde r
t he
Apr i l 29 , 1 98 5 . a nd Pr o mi s s o r y Not e dat e d Aug us t 1 , 19 8 7 , pl us a ny
a c c r ue d I nt e r e s t t he r e o n. a r e pa I d by Se l l e r t o Al pha i n f ul l .
subject
t o t he pr o v l s l on- t ha t any l o a n amo unt o ut s t a ndi ng
as o f
De c e mbe r 3 1 , 1 9 8 8 ~1 1 1 b e c o me i mme d i a t e l y due and pay a bl e t o g e t he r
wi t h a l l I nt e r e s t a c c r ue d t he r e o n t o De c e mbe r 31 , 1 98 8 , wi t hl n t e n
( 10 ) day s of t he da t e o f wr i t t e n not I c e f r o m Al pha o f t he t o t a l
a mo unt due . "
( a ) Lo an Agr e e me n t a nd Pr omi s s o r y Not e dat e d Apr i l 2 9 , 1 9 8 5 ,
t ndl c at l ng a Se ve nt y Ff v e Tho us a nd Dol l a r ( $ 7 5 , 0 0 0) c a s h l o a n,
s ha l l be r e pa l d a t Twe l v e Pe r c e nt ( 1 2%) s l mpl e annual I nt e r e s t
a s f o l l o ws :
I)
One Do l l a r ( $1 . 00 ) p e r ki l o gr a m o f Pl a s ma pur c ha s e d by
Al pha f r o m Se l l e r ' s Fa ye t t e v l l l e , Ar ka ns a s Ce nt e r ; a nd
1 1)
Fi f t y Ce n t s ( $ 0 . 50 ) pe r ki l o g r am o f Pl a s ma pur c ha s e d
by Al pha f r om Se l l e r ' s No r t h Ll t t l e Roc k, Ar ka ns a s a nd Pi ne
Bl uf f , Ar ka ns a s Ce nt e r s , whi c h s e t o f f s and de duc t i o ns s ha l l
be a ppl ! e d t owa r d t he Lo a n Amo unt af t e r t he - Pr o mi s s o r y No t e
da t e d Aug us t 1, 1 9 87 , i s r e pai d t o Al pha by Se l l e r I n f ul l .
l l i ) One Do l l a r ( $ 1. 0 0 ) pe r ki l o g r a m o f Pl a s ma pur c ha s e d by
Al pha f r o m Var ne r Pl a s ma Ce nt e r , Inc. - Ar ka ns a s De par t me nt
o f ‘ Co r r e c t I o ns , Cumnl ns Unt t , Gr a dy Ar ka ns a s a nd Ar ka ns as
De pa r t me nt
of
Co r r e c t l ons Pi ne Bl uf f
Dl ag no s t I c
a nd
Wo me n' s Uni t , Pt ne Bl uf f , Ar ka ns a s Ce nt e r s .
l ndl c a t i ng
a
Aug us t 1 , 19 8 7 ,
da t e d
No t e
Pr o mi s s o r y
b)
Twe nt y- Two Tho us a nd Fl v e Hundr e d Se v e nt y Fo ur 6 3 1 10 0 Dol l a r s
( $2 2 . 57 4 . 63 ) a mo unt o we d o n do wng r ade d pl as ma , s ha l l be r e pa l d
ul t ho ut I nt e r e s t as f o l l o ws :
Fl f t y Ce nt s ( $ 0 . 50 ) pe r kl l o g r am o f Pl a s ma pur c ha s e d
1)
by Al pha f r o m Se l l e r ' s No r t h Li t t l e Ro c k, Ar ka ns a s a nd Pi ne
Bl uf f , Ar ka ns a s Ce nt e r s . "
c
.

- 2-

The

a me ndme nt s

Ame ndme nt

Numbe r

Agr e e me nt

I n f ul l

to

One

t he
s ha l l

Pl as ma
be

de e me d

to

whi c h

be

ar e

s et

i nc or po r a t e d

f or t h
I nt o

fn

t he

t hi s

Pl a s ma

by t he r e f e r e nc e he r e l n and s ha l l be f ur t he r de e me d t o be a n

I nt e gr a l par t t he r e o f

as t ho ug h f ul l y s e t f o r t h t he r e l n.

c o ndl t l o ns of t he Pl as ma Agr e e me nt
I N WI TNESS WHEREOF,
Ame ndme nt

Ag r e e me nt

Al l

ot he r

t e r ms

a nd

s ha l l r e ma i n i n f ul l f or c e a nd e f f e c t .

t he pa r t i e s he r e t o ha v e e nt e r e d l nt o a nd e x e c ut e d t hi s

Numbe r One o n t he da t e s e t f o r t h be l o w.

PI NE BLUFF BI OLOGI CAL PRODUCTS,

JFK: 3077L
03/31laa
-3-

I NC.

AMENDMENT NUMBER ONE
TO
AGREEMENT FOR THE PURCHASE AND SALE
OF BLOOD PLASMA
. BETWEEN
ALPHA THERAPEUTI C CORPORATI ON
AND
VARNER PUSHA

CENTER,

INC.

(PINE BLUFF AND GRADY)

Thi s Ame ndme nt

Numbe r One

The r a pe ut i c Co t pot a t l o n,

1 s ma de

a Cal l f ot nl a

a nd e nt e r e d
Co r por a t i o n.

I nt o by a nd be t we e n Alpha
wi t h I t s pr l nc l pal pl a c e o f

r -

bus i ne s s a t 55 5 5 Va l l e y Bo ul e v ar d,
ref erred

to

"Al pha ")

as

a nd

c o r por a t i o n wi t h a pr i nc i pa l

Lo s Ang e l e s ,
Va r ne r

pl a c e

of

Ca l l f o r nl a

Pl a s ma

9 0 03 2 ( he r e f na f t e r
Inc.,

Ce nt e r ,

bus l ne s s _ a t

an

51 0 Mul be r r y

Ar ka ns a s

St r e e t ,

Pi ne

Bl uf f , Ar ka ns a s 7 16 0 1 ( he r e i na f t e r r e f e r r e d t o a s "Se l l e r ") .

WI _TNESSETH:
__
_ __ _ __ _

t he

CI HEREAS, on Aug us t

5,

Pur c ha s e

of

a nd Sa l e

1 98 7 Al pha and Se l l e r e nt e r e d
Bl o o d

Pl a s ma

( he r e i na f t e r

I nt o a n Ag r e e me nt

ref erred

to

as

f or

"Pl a s ma

.

Agr e e me nt ") ,

a nd

CI HEREAS, t he

pa r t i e s

de s i r e

t o make

c e r t ai n c hang e s

Ag r e e me nt t o be c ome e f f e c t i v e f r o m Ma r c h 7 ,

lion,

THEREFORE,

I n c o ns f de r a t l o n of

I n a nd t o t he Pl a s ma

1 9 88 .

t he f o r e g o l ng

L
c

a nd s ubj e c t

-l-

MDLTPL4A-0345

t o t he t e r ms