Vilke Et Al Literature Review Er Evaluation After Taser Use 2011
Download original document:
Document text
Document text
This text is machine-read, and may contain errors. Check the original document to verify accuracy.
The Journo.l of Emergency Medicine. Vol••• No••• pp. 1-7. 2011 Copyright is) 2011 American Academy of Emergency Medicine • . Printed in .be USA. All rights ~erved 073646791$ - see front mailer ELSEVIER doi:10.l016/j.jemermed.2010.1~.019 ~~~ Clinical ~ Reviews EMERGENCY DEPARTMENT EVALUATION AFTER CONDUCTED ENERGY WEAPON USE: REVIEW OF THE LITERATURE FOR THE CLINICIAN Gary M. Vilke, MD,* William P.Bozeman, MD,t and Theodore C. Chan, MO* 'D.epartment of Emergency Medicine, University of Cal~omla at San Diego Medical Center, San Diego. Califomia, and . tWake Forest University, Winston Salem. North Carolina Reprint Address: Gary M. Vilke, MD, Department of Emergency MecflCine. UC San Diego Medical Center, 200 West Arbor Drive, Mailcode #8676, San Diego,. CA 92103 o Abstract-Background: Conductive energy weapons (CEWs) al'e used daily by law enfol'eement, and patients are oCten brought to an emergency department (ED) for medical clearance. Study Objectives: To review Ihe medical literature on the topic of CEWs and to offer evidence-based recommendations to Emergency Physicians for evaluation and treatment of patients who have received a CEW exposure. Methods: A MEDLINE literature search froln 1988 to 2010 was performed and limited to human studies p»;blished from January 1988 to January 20, 2010 for English language articles with the following keywords: TASER, conductive energy device(s), electronic weapon(s), conductive energy weapon(s), non-lethal weapon(s), conducted energy device(s), conducted. energy weapon(s), conductive electronic device(s), and electronic control devlce(s). Studies identified then underwent a structured review from which results could be evaluated. Results: There were 140 articles on CEWs screened, and 20 appropriate articies were rigorously reviewed and recommendations given. These studies did not report any evidence of dangerous laboratory abnormalities, physiologic changes, or.immediate or delayed cardiac ischemia or dysrhythmias after exposure to CEW electrical discharges of up to 15 s. Conclusions: The current medical literature does not support routine performance of laboratory studies, electrocardiograms, or prolonged ED observation or hospitalization for ongoing cardiac monitoring after CEW exposure in an otherwise asymptomatic Position Paper Approved by the American Academy of Emergency Medicine Clinical Guidelines Committee awake and alert patient. Emergency Medicine © 2011 American Academy of o Keywords-conductive energy weapons; TASER; emergency deparbncnt; treatment INTRODUCTION Use of conducted energy weapons (CEWs) such as the TASER (TASER International Inc., Scottsdale, AZ) in, cludes delivery of a series of brief electrical pulses, which result in pain and muscular contractions. The pulses may be delivered via a pair of sharp metal probes fired from the device, commonly referred to as "probe mode," or by direct contact with the front of the dcvice, commonly referred to as "drive stun" or "touch stun" mode. Current practice in managing patients who present to the Emergency Department (ED) 'after being exposed to a CEW varies from place to place and by' individual practitioners. Some hospitals have the practice of admitting all patients who were exposed to a TASER to the hospital for overnight telemetry monitorlhg, whereas other systems allow Emcrgcncy Medical Scrvices providers to remove the darts in the field and the police take the patient directly to jail without ever going to an ED. This article seeks to review the medicallilerature on the topic of CEWs and to offer evidence-based recommendations to Emergency Physicians for evaluation and RECEIVED: 16. August 2010; FINAL SUBMISSION RECEIVED: 9 October 2010; ACCEPTED: 31 October 2010 EXHIBIT 48 TI-TURNER50008 Case 3:10-cv-00125-RJC-DCK Document 46-13 Filed 02/25/11 Page 1 of 7 G. M. Vilka at al. treatment of patients who have received a CEWexposure. The clinical question being asked was: Do patients who present to an ED after a CEW exposure need any specific radiographic or laboratory evaluation or any specific monitoring based solely because a CEW was used? This work was done at the request of and published as a position statement by the American Academy ofEmergency Medicine Clinical Guidelines Committee. MATERIALS AND METHODS Independent review of the articles as well as discus. sion and joint review by the au~ors was undertaken to answer the clinical question.. Thc references were sorted intQ 3 categories: supportive. neutral. and opposed. A table was constructed to assign the supportive references to the appropriate location using both the Grade'of Evidence and' the Quality of Evidence. Finally, recommendations were made· based on the reo' view of the literature and assig!1ed a level of recommendation. which are defined in Table 3. This was a structured review of the literature on the topic of CEWs. A literature search of the National Library of Medicine's MEDLINE database's PubMed system was performed and limited to studies published from Janu~y 1988 to January 20, 2010 written in the English language. Keywords used in the search were: TASER, conductive energy device(s), electronic weapon(s), conductive energy weapon(s), non-lethal weapon(s), conducted energy device(s), conducted energy weapon(s), conductive electronic device(s), and electronic control device(s). After searching the articles found from these key word parameters! the Reference sections were also reviewed for additional articles. Studies included for the final review were limited to randomized controlled trials, clinical trials, prospective and retrospective cohort studies, and meta-analyses in human subjects. Case reports, case series, and general· review articles were not included for the selection criteria for formal rigorous review. The final list of all of the articles was assessed independently by two emergency medicine physicians to determine the c)assification of the article and deem whether appropriate'for formal review. . Each of the articles selected underwent a Grade of Evidence Review. Each of the selected articles was subjeCted to detailed rcview 6y all three authors. The level of the evidence was assigned a grade using the definitions as noted in Table 1 and were based on reference focus, specific research design, and methodology. Each of the selected articles was also subjected to detailed review and assigned a Quality Ranking based on a critical assessment with regards to quality of the design and methodology. Thi~ included Design Consideration (e.g., focus, model structurc, prescnce of controls) and Methodology Consideration (actual methodology utilized). The definitions of the Quality Ranking scores are included in Table 2. RESULTS The findings of the original key word search in MEDLINE are noted in Table 4 under the column u# ALL references." Combining these references resulted in 140 unique articles on CEWs. From these original 140 articles, the Reference sections were also reviewed, and ,no further novel articles were identified. It was noted that not all articles that were captured with these key words involved CEWs. which is why there were 145 articles found using the key words "conductive electronic devices" but only 140 unique articles identified on. the topic. Studies included for the final review were limited to randomized controlled trials, 'clinical trials, prospective and retrospective cohort studies, and meta-analyses. The numbers of references yielded by the various search parameters are included in the column labeled "final review" in Table 1. There were a total of20 articles deemed appropriate for intensive critical review based on their suspected relevance to the clinical question (1-20). These 20 articles include: randomized controlled trials (n:; 2). prospectivc controlled trials (n = 2), prospective cohort studies (n 13), and retrospective cohort studies (n == 3) (Table 5). Table 6 includes the Grade of Evidence and the Quality of Evidence for each of the articles reviewed. The references were sorted into three categories: supportive, neutral, and opposed. All were supportive; none were classified as neutral or opposed. ' = Recommendation 1: Cardiac Monitoring and Electrocardiogram Screening after CEW Use Levelo/recommendation: Class A. The current human literature has not found evidence of immediate or delayed cardiac ischemia or dysrhythmia.~ after CEW exposures. Table 1. The Definitions of the Grades of Evidence of 1he Articles Grade A GradeB GradeC GradeD Randomized clinical trials or meta-analyses (multiple clinical trials) or randomized clinical trials (smaller trials), directly addressing the review issue . ., • Randomized clinical trials·or meta-analyses (multiple clinical trials) or randomized clinical trlal.s (smaller tnaIS).lndlrectly addressing the review Issue Prospective. controlled, non-randomized, cohort studies . Retrospective, non-randomized, cohort or case-control stUdies TI-TURNERS 0009 Case 3:10-cv-00125-RJC-DCK Document 46-13 Filed 02/25/11 Page 2 of 7 Ev~ation after CEW Use 3 Table 2. The Definitions of the Quality Ranking Scores of the Articles Ranking Outstanding Good Adequate Poor Unsatisfactory Design Consideration Present Appropria~e Appropriate Adequate with possible bias Limited or biased Questionable/none of up to 15 s. Therefore, the medical literature does not support routine performance of electrocardiograms (ECGs), prolonged ED observation, or hospitalization for ongoing cardiac monitoring after CEW exposure in an otherwise asymptomatic awake and alert patient with a short duration « 15 s) o/CEWexposure. Studies have looked for dysrhythmias during and immediately after CEW use (1,11-14,19,20). There have been no reports of ectopy, dysrhythmia, QT prolongation, interval changes, or other ECG changes immediately afler CEW use. Additionally, studies have looked at delayed monitoring findings and there have been no changes in ECGs 60 min or longer post CEW use (13,17,20). Studies have also looked at serial troponin levels as a marker of cardiac injury or ischemia. A number of stud~ ies have looked at troponin levels at 6 h post CEWactivation, and all levels except one have been normal (12,13,15,20). The one study that showed elevated troponin was on a healthy young male subject who received a 5-s TASER activation (13). The troponin I values all were < 0.3 nglmL, except a single value of 0.6 nglmL at the 24-h draw, which had been normal at the 16-h draw, and returned to normal within 8 h of the reported elevation. The subject was evaluated at the hospital Methodology Consideration Present Both Com;iderations Present Appropriate Appropriate Adequate LImited Questionable/none Yas, both present No, either'present No, either present No, either present No, either present· by a cardiologist and showed no evidence of myocardfal infarction or cardiac disability. His inpatient evaluation included a treadmill stress test (Treadmill Myoview test utilizing standard Bruce protocol with a double product of 24,335 achieved) and a rest/adenosine-augmented stress-gated tomographic myocardial perfusion study utilizing Tc99 m radiopharmaceutical injection. The results of both tests were interpreted as normal. Echocardiograms during CEW use have also shown no abnormalities during activation to suggest electrical capture or'structural cardiae damage (3,11): Recommendation 2: Laboratory Testing after CEW Use Levelo/recommendation: Class A. The current human literature has not found evidence of dangerous laboratory abnormalities or physiologic changes after CEW exposures of up to 15 s. Therefore, the medical literature does not support routine performance oflaboratory studies, prolonged ED observation, or hospitalizalion for ongoing labaratory monitoring after a short duration 0/ CEWexposure « 15 s) in an otherwise asymptomatic awake and alert patient. Studies have not shown any clinically significant changes in electrolyte levels or renal function in subjects with up to 15-8 CEWactivations (9,13, l8,20):There have Table 3. Definitions for Recommendations Criteria for Level of Recommendation Level of Recommendation Class A Recommended with outstanding evidence Class 6 1 • • • • • • • ,. • Class 62 • Optional or alternativc approach ClassB Acceptable and appropriate with gOOd evidence ClassC Not acceptable or not appropriate Class Indetenninate Unknown • • • • Acceptable Safe Useful Established/definitive 'Accepiable Safe Useful Not yet definitive Standard approach Unacceptable Unsafe Not useful Minimal to no evidence Mandatory Evidence o D • • • • • • • • • • • • Level ME grade Outstanding quality Robust All positive Level ME grade lacking Adequate to Good quality Most evidence positive No evidence of harm Higher grades of evidence Consistently positive Lower grades of evidence Generally, but not consistently, positive No positive evidence Evidence of hann • Minimal to no evidence TI-TURNER50010 Case 3:10-cv-00125-RJC-DCK Document 46-13 Filed 02/25/11 Page 3 of 7 G. M. Vilke et al. 4 Table 4. All English-language Articles Found with the Following Search Parameters Search Parameter Conductive electronic devices TASER Conductive energy devices Conductive electronic device Conductive energy device Electronic weapon Electronic weapons Conducted energy weapons Non-lethal weapons Non-lethal weapon Electronic control devices Electronic control·device Conducted energy weapon Conductive energy weapon Conductive energy weapons Conducted energy device Conducted energy devices #I All References II Anal Review 145 137 113 112 87 o 15 4 o 4 8 70 54 8 32 6 30 22 12 11 4 3 3 o o o o o o 1 3 DISCUSSION 3 o o been mild but clinically insignificant elevations in lactate levels with CEW activations. However, these have been demonstrated to be of a smaller magnitude relative to other forms of physical exertion with a similar duration (8,10,12,13,18,20). Acid base status has been evaluated and has not shown any significant pH shifts for a 5-1> CEW activation (13,18,20). Similar findings with mild transient pH shifts were noted in CEW use for longer durations of application up to IS s (9). Recommendation 3; Evaluation after Use Drive Stun or Touch Stun Mode nerves, and bones. Musclc contractions due to the CEW may produce spinal compression fractures and other soft tissue injuries. Falls may occur from loss of muscular control and protective reflexes, resulting in blunt trauma. Literature review indicates that significant injuries due to this mechanism are rare, occurring in<O.S% of realworld deployment in subjects (2,16). As above, routine BCG, cardiac monitoring, laboratory testing, or other forms of evaluation specific to the electrical component of short-duration CEW use are generally unnecessary. 0/ CEW in Level 0/ recommendation: Class B. For patients who have undergone drive stun or touch sllln CEW exposure, mcdical scrccning should focus on local sldn effects at the exposure site, ~hich may include local skin irritation or minor contact bums. This recommendation is based on a literature review in which thousands of volunteers and individuals in police custody have had drive stun CEWs used with no untoward effects beyond local sldn effects. As above, routine ECG, cardiac monitoring, laboratory testing, or other forms of evaluation specific to the electrical component of short-duration CEW usc are generally unnecessary. Recommendation 4; Evaluation after Use oj CEW in Probe Mode . Level o/recommendation.. Class B. For patients who have u.ndergone probe mode CEW exposure, medical screening should focus on probe penetration sites, potential injuries due to muscle contractions, and potential trauma due to falls. CEW probes may strike the eyes, or penetrate skin and nearby superficial structures such as vessels, CEWs are commonly used by police as an intermediate force option. Civilian models of CEWs are also available to the public. Patients may be brought to EDs for medical evaluation after CEWexposure. The primary goal in conducting this literature search was to identify whether routine monitoring, ECG, with or without laboratory tests are necessary for a patient who presents after receiving an electrical discharge from a CEW.·· Our evaluation considered both techniques in which a CEW can be used. They are the drive or touch stun mode, and the probe mode. In the drive stun mode, the tip of the device is placed in contact with the subject and locally conducts energy across the two probes that are present on the tip of the device. This mode typically causes local painful stimuli. The other technique is the "probe mode," which uses two shaw metal darts that are shot from a distance into the subject or the subject's clothing, causing cncrgy to arc a greater distance across thc two probes. If there is enough of a probe spread, generalized muscle contraction, sometimes termed "neurom\!scular incapacitation," is produced. This may result in the subject falling.if he or she is in a standing position. There are case reports of injuries sustained directly from the darts, such as ocular, skull, or genital penetration (21,22). Other case reports of spinal compression fractures, presumably from intcnse muscle contractions of thc back musculature in subjects withosteopenia, have been documented (23,24). There are no studies demonstrating the effects on pregnant women, so physicians will need to make clinical decisions on the need for fetal assessment and monitoring based on the type of CEW use, location, and patient prescntation. As noted above, the litcraturc review for this clinical guideline focused on studies that involved rigorous methodologies to cvaluate the physiologic effects of CEWs in humans. We did not include specific case reports or case serie.~ which in and of themselves cannot support any causal connection between CEWs and physiologic changes. We also did not include animal studies, which TI-TURNER5 0011 Case 3:10-cv-00125-RJC-DCK Document 46-13 Filed 02/25/11 Page 4 of 7 m' ~ Case 3:10-cv-00125-RJC-DCK Document 46-13 cSl) g ~ ~ ~ Table 5. Details of the 20 Reviewed Articles List # 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Article Information Grade Quality Bozeman WP et al. Immediate cardiovascular effects of the Taser X26 conducted electrical weapon. Ernerg Med J 2009 C Good Bozeman WP et a!. Safety and injury profile of conducted electrical weapons used by law enforcement officers against orimlnal 0 Good suspects. Ann Emerg Med 2009 Dawes OM et at Echocardiographlc evaluation ofTASER)(26 probe deployment into the chests of human volunteers. Am J Emerg C Good Mad 2010 Dawes DM et al. ElectriCal characteristics of an electronic control device under a physiologic load: Ii brief report Pacing Clin C Good Electrophysiol 2009 ' Dawes DM et al. 15-5econd conducted electrical weapon exposure does not cause core temperature elevation in nonC Good environmentally stressed resting adults. Forensic Sci Int 2008 Dawes D et aI. The neuroendocrine effects of the TASER X26: a brief report. Forensic Sci Int 2009 B Good Eastman AL et at Conductive electrical devices: a prospective, population-based study of the medical safety of law enforcement use. J Trauma 2008 ' Ho JD et aI. Prolonged TASER use on exhausted humans does not worsen markers of acidosis. Am J Ernerg Med 2009 Ho JD et al. Lactate and pH evaluation In exhausted humans with prolonged TASER)(26 exposure or continued exertion. Forensio Scllnt2009 Ho JD et al. Absence of electrocardiographio change after prolonged appllcatJon of a conducted electrical weapon in physically exhausted adults. J Emerg Med 2009 Ho JD et al. Echocardiographic evaluation of a TASER-X26 application in the ideal human cardiac axis. Acad Emerg M~d 2008 Ho JD e~ al. Respiratory effect at-prolonged electrical weapon application on human volunteers. ~d Emerg Med 2007 Ho JD et el. Cardiovascular and physiologic effects of conducted electrical weapon discharge in resting adults. Acad Emerg Med 2006 ' . Levine SO et at Cardiac monitoring of human subjects exposed to the taser. J Emerg Med 2007 Sloane CM et aI. Serum troponln I measurement of subjects exposed to the Taser X-26. J Emerg Med 2008 Strote J et al. Conducted electrical weapon use by law enforcement: an evaluation of safety and injury. J Trauma 2009 Filed 02/25/11 Page 5 of 7 17 VanMeenen KM et al. Cardiovascular evaluation of electronic control device exposure in law enforcement trainees: a multisite study. J Occup Environ Med 2010 18 Vilke GM et al. Physiologic effects of the TASER after exercise. Acad Emerg Med 2009 o Adequate C Good B Good 0 Good ~ Design, Size (!) Prospective cohort (n = 2~) Retrospective cohort (field use)(n = 1201) Prospective cohort (n = 10) Prospective cohort (n = 9) Prospective controlled trial '(n=32) Prospective randomized controlled trial (n = 52) Retrospective cohort (field use) (n = 426) Prospective cohort (n = 38) Prospective randomized controlled trial (n = 40) Prospective coho,rt (n,= 25) C Good Prospective cohort (n = 34) C OutstandingProspective cohort (n = 52) C OutstandingProspective cohort (n = 66) C Good C Good D Adequate C Good Prospective cohort (n '" 105) Prospective cohort (n 66) Retrospective cohort (Field use){n = 1101) Prospeqtive cohort (n = 118) = C OutstandlngProspective controlled trial (n=25) 19 Vilke GM et aI. Twelve-lead electrocardiogram monitoring of subjects before and after voluntary expoSure to the Taser X26. Am J C Good Prospective cohort, (n 32) Emerg Med 2008 20 Vilke GM et al. Physiological effects of a conducted electrical weapon on human subjects. Ann Emarg Med 2007 C Outstanding Prospective cohort (ri 32) = = -i I -i C ;0 Z m ;0 0'1 0 0 ...lo. I\.) en G. M. Vilke et al. 6 Table 6. Supportive .Evidence (Article # Referenced) Quality/Grade Outstanding Good Adequate A o B c 6,9 12,13,18,20· 1,3,4,5,8.10,11,14,15,17.19 E F 2 7,16 Poor Unsatisfactory There were no neutral or opposed references. are often more limited in .scope and have questionable applicability to clinical human findings. Recommendations in this review are limited to CEW exposure durations of 15 s or less. This reflects the exposure durations commonly used in the exiSting human literature and will apply to the large majority (> 90%) of subject~ against whom CEWs are used by police officers. Although several reports have included exposure durations of 20-45 s and have not demonstrated concerning cardiac or physiologic effects, collectively this small body of literature is inadequate to support guidelines on medical screening after longer duration exposures. Therefore, until confirmatory studies of adequate power are available, clinicians should use their own judgment regarding the need for screening tests in this popUlation. It is important to point out that these recommendations focus solely on the issue ofCEWs and their physiologic effects on humans. Clinical evaluation and testing ~ay very well be warranted when evaluating patients after CEW application, not due to the CEW exposure, but as a result of the patient's underlying condition such as alcohol or drug intoxication, altered mental status, physical exhaustion: excited delirium, or psychiatric conditions that precipitated the application of the CEW in the first place. conditions like intoxication, prolonged struggling, altered mental status, or symptoms of excited delirium syndrome may also be present in patients exposed to CEWs, although the CEW does not seem to be the precipitating factor. Presence of these findings should prompt additional evaluation or treatment of the.underlying condition as clinically warranted. For CEW activations in' the probe mode, patients -should be screened for injuries related to the dart penetration or surface bums due to CEW ilse, as well as injuries associated with falls and muscle contractions. Among patients who had a CEW activation in drive stun or touch stun mode, evaluation should focus on skin manifestations, which are typically limited to surface bums, also called signature marks. REFERENCES 1. Bozeman WP. Barnes DG Jr, Winslow JE 3rd, Johnson IC 3rd. 2. 3. CONCLUSIONS The current human literature has not found evidence of dangerous laboratory abnormalities, physiologic changes, or immediate Of delayed cardiac ischemia or dysrhythmias after exposure to CEW electrical discharges of up to 15 s. Therefore, the current medical literature does not support routine perfomlance of laboratory studies, ECGs, or prolonged ED observation or hospitalization for ongoing cardiac monitoring after CEW exposure in an otherwise asymptomatic awake and a lert patient. Testin'g for cardiac conduction abnormalities or injury, or other physiologic effects of CEWs may be appropriate in individual cases based on medical history such as history of cardiac disease or symptoms like chest discomfort, shortness of breath, or palpitations suggestive of cardiac issues, pain suggesting muscle contraction injuries, or prolonged CEW exposure> 15 s. Coexisting 4. 5. 6. 7. 8. 9. 10. Phillips CR. Alson R. Immediate cardiovascular effects or the Taser X26 conducted electrical weapon. Emerg.MOO J 2009;26:567-70. Bozeman WP, Hauda WE 2nd. Heck JJ. Graham DD Jr, Martin BP. Winslow JE. Safety and injury' profile of conducted electrical weapons used by law enforcel11ent ofticers against criminal suspects. Ann Emerg Med 2009;53:480-9. . Dawes DM. Ho m. Reardon RF, Miner JR. Echocardiograpnic evaluation ofTASER X26 probe deployment into the-chests of human volunteers. Am 1 Emerg Med 2010;28;49-55. Dawes DM. Ho lD. Kroll MW, Miner JR. Electrical characteristics of an electronic control device under a physiologic load: a brief report. Pacing Clin Electrophysiol 2010;33:330-6. Dawes DM, Ho.JD, Johnson MA, Lundin E, Janchar TA. Miner JR. IS-Second conducted electrical weapon exposure does not cause core temperature elevation in non·environmentally stressed resting adults. Forensic Sci InI2008;176:253-7, Dawes D. Ho J, MinerI. The ncuroendocrine effecls of the TASER X26: a briefrcport. Forensic Sci InI2009;lS3:14-9. Eastman AL. Melzger JC, Pepe PE, et al. Conductive electrical devices: a prospective, population-based study of the medical safety oflaw enforcement use. J Trauma 2008;64:1567-12. Ho m, Dawes DM. Bullman LL. Moscati RM. Janchar TA. Miner JR. Prolonged TASER use on cxhau..ted humans does nol worsen markers ofncidosis. Am J Emerg Med 2009;27:413-S. Ho m, Dawes DM. Cole JB, HOllinger IC, Overton KG. Miner JR. Lactate and pH evaluation in exhausted humans with prolonged TASER X26 exposure or continued exenion. Forensic Sci Int 2009;190;80-6. . Ho 10, Dawes DM, Heegaard WG. Calkins HG, Moscali· RM. Miner JR. Absence of electrocardiographic change after prolonged application of" a conducted eJeclrical weapon in physically exhausted adults. J Emerg Med 2009 May 12: IEpub ahead of printJ. TI-TURNER50013 Case 3:10-cv-00125-RJC-DCK Document 46-13 Filed 02/25/11 Page 6 of 7 Evaluation after C8N Use 7 11. Ho ro. DaweS DM. Reardon RF. et aI. Ecl1ocardiographic evalualion of a TASER-X26 application in the ideal buman cardiac axis. Acad Emerg Med 2008;15:838-44. 12. Ho JD. Dawes DM. Bultman LL, et aI. Respiratory effect of prolonged electrical weapon application on human volunteers. Acad Emerg Med 2007;14:197-201. 13. Ho ID. Miner JR. Lakireddy DR, Bultman LL, Heegaard WO. Cardiovascular and physiologic effects of conducted electrical'weapon discharge in resting adults. Acad Emerg Med 2006;13:S89-9S. 14. Levine SD, Sloane eM, Chan TC, Dunford N, Vilke GM. Cardiac moniloring of human subjects exposed 10 the taser. J Emerg Med 2007;33:113-7. 15. Sloane CM, Chan Te, Levine SD, Dunford IV, Neuman T. Vilke GM. Serum tropanin'l measuremenl of subjects exposed to the Taser X-26.1 Emert Med 2008;35:29-32. 16. StrOle I, Walsh M, Angelidis M. Basla A, Hutson HR. Conducted electrical weapon use by law enforcement: an evaluation of safety and injury. J Trauma 2010;68:1239-46. 17. VanMeenen KM, Cberniack NS, Bergen MT, el al. Cardiovascular evaluation of electronic control device expOsure in law enforce· 18. 19. 20. 21. 22. 23. 24. ment trainees: a multisite study. J Occup Environ Med 2010;52: 197-201. Vilke OM. Sloane eM. Suffecool A, et al. Physiologic effects of the TASER after exercise. Aead Emerg Med 2009;16:71J4....]0. Vilkc OM, Sloane C, Levine S, Neuman T, Castillo E. Chan TC. 1Welve-lead electrocardiogram monitoring of subjects before and after voluntary exposure to the Taser X26. Am J Emerg Med 2008;26: 1-4. Vilke GM, Sloane CM, Bouton KD, et a!. Physiological effects of a conducted electrical weapon on human sUhjccts. Ann Emerg Mod 2007;50:569-75. Rehman TV, Yonas H. Case report: intracranial penetration of a TASER dart. Am J Emerg Mcd 2007;25:733. Ng W. Cbehade M. Taser penetrating ocular injury. Am] OphlhalmoI200S;139:113-S. Sloane CM. Chan Te, Vilke GM. Thoracic spine compression fracture after TASER activation. ] Emers Med·2008;34:283-5. Winslow JE. Bozeman WP, Fortner Me, Alson RL. Thoracic compression fractures as a result of shock from a conduc.ted energy weapon: a case. report. Ann Emerg Mcd 2007;50:584-6. ARTICLE SUMMARY 1. Why is this topic important? Conductive Energy Weapons (CEWs) are used daily by law enforcement and patients are often brought to Emergency Departments (ED) for medical clearance. 2. What does this review attempt to show? The clinical question being asked was: Do patients who present to an Emergency Department after a. CEW exposure need any specific radiographic or laboratory evaluation or any specific monitoring based solely because a CEW was used? 3. What arc the key findings? These' studies did not report any evidence of dangerous laboratory abnormalities, physiologic changes, or immediate or delayed cardiac ischemia or dysrhythmias after exposure to CEW electrical discharges of up to 15 seconds. 4. How is patient care impacted? There might be more efficient use of the emergency department and ICU beds. TI-TURNER50014 Case 3:10-cv-00125-RJC-DCK Document 46-13 Filed 02/25/11 Page 7 of 7